Journal: Aging Cell
Article Title: Age‐related changes in human skeletal muscle microstructure and architecture assessed by diffusion‐tensor magnetic resonance imaging and their association with muscle strength
doi: 10.1111/acel.13851
Figure Lengend Snippet: Scatter plots showing muscle architecture parameters versus age (top panel) and peak concentric, isokinetic knee extension, and flexion torques, obtained with an angular velocity of 30°/s (bottom panel). Results are shown separately for the rectus femoris (RF) and biceps femoris longus (BFL) muscles, with knee extension torques being reported for the former and flexion torques for the latter. Simple, unadjusted linear regressions show significant associations between curvature, fascicle length, and physiological cross‐sectional area (PCSA) and age, particularly in the RF. Positive associations are seen between pennation angle and torque and PCSA and torque, in both muscles. No clear trends are apparent between fiber curvature or fascicle length and torque. Regression lines and 95% confidence intervals are shown, along with unadjusted model statistics. See Table for multiple regression statistics including sex as a covariate.
Article Snippet: The strength of each participant's left leg was evaluated during isometric and concentric knee‐extension and flexion exercises using an isokinetic dynamometer (Biodex Multi‐Joint System‐PRO with Advantage Software v4X, Biodex Medical Systems, Inc.).
Techniques: Muscles